Mouse anti-Human Alpha Fetoprotein (AFP) (unconjugated), Clone A-013-01, IgG1a, Ready-to-use
Ready-to-use Antibody for Immunohistochemistry
Alpha-fetoprotein (AFP) is a fetal globulin with a molecular weight of approximately 70 kDa. AFP is synthesized in fetuses in relatively high concentrations in the embryonic yolk sac, gastrointestinal tract and liver. During normal pregnancy, it is detectable in both maternal and fetal serum. Shortly after birth, AFP levels drop to a very low level (20ng/ml).
Increasing AFP levels in adults (outside of pregnancy) are usually associated with hepatocellular carcinoma or yolk sac tumor (testicular or pineal organ). The increasing AFP synthesis rate of malignant hepatic cells is interpreted as a return of the cells to the more active fetal stage.
Alpha Fetoprotein (AFP)
|Host / Source||
Human Alpha Fetoprotein (AFP)