Mouse anti-Human CEA (unconjugated), Clone 85A12, IgG1, Ready-to-use
Ready-to-use Antibody for Immunohistochemistry
CEA is a phospho-gycoprotein and a component of the glycocalix of the embryonic endodermal epithelium. It is a member of the immunoglobulin superfamily and the CD66 molecules (MW 170 to 200 kDa) expressed by neutrophilic granulocytes. CEA is present in cell extracts of many carcinoma types, especially intestinal tumors. In serum, CEA is determined as a tumor marker whose concentration is reported to correlate well with tumor mass. CEA expression is usually a sign of de-differentiation in gastric and intestinal carcinomas.
|Host / Source||