Mouse anti-Human Choriongonadotropin (ß-HCG) (unconjugated), Clone SC1, IgG1, Purified
Concentrated Antibody for Immunohistochemistry
Background
hCG is a 40 kDa glycoprotein composed of two subunits, α and β. The α subunit is common for hCG, LH, follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH), while the β subunit is unique for hCG although its amino acid sequence partially is identical with that of the β subunit of LH. hCG is the most important marker of gestational trophoblastic cells, being present in syncytiotrophoblastic cells and cells of the intermediate trophoblast but absent in cytotrophoblasts. hCG expression has also been demonstrated in some non-trophoblastic tumours, e.g. in 14% of patients with hepatocellular carcinoma.
In pregnancy, the serum hCG concentration increases at an exponential rate initially, then peaks at around 100 kIU/L at about the tentafter conception. The concentration decreases about ten fold over the next several weeks followed by a small increase near term.
Synonyms
Choriongonadotropin, hCG Beta, Chorionic Gonadotropin Beta
| Specificity | ß-HCG (Choriongonadotropin) |
|---|---|
| Species Reactivity | Human |
| Host / Source | Mouse |
| Isotype | IgG1 |
| Application | IHC-F, IHC-P |
| Clone | SC1 |
| Antigen | Human ß-HCG (Choriongonadotropin) |
| Quantity | 0, 5 mg |
| Format | Purified |
| Storage Temperature | 2-8 °C / -20 °C |
| Shipping Temperature | 2-8 °C |
Datasheet