Mouse anti-Human Cytokeratin-7 (CK7) (unconjugated), Clone OV-TL 12/30, IgG1, Purified
Concentrated Antibody for Immunohistochemistry
Background
Anti-cytokeratin 7 reacts with proteins that are found in most ductal, glandular, transitional, and biliary duct epithelial cells. Cytokeratin 7 (CK7) labeling can help distinguish between lung, breast carcinomas, and urothelial carcinomas that typically stain positive, and colon and prostate carcinomas that typically lack CK7 expression. CK 7 is a common marker of primary lung adenocarcinomas (almost all cases) with a lower specificity since it is also observed in other primary lung carcinomas and non-pulmonary carcinomas. Anti-cytokeratin 7 has also been useful in the differential diagnosis of ovarian neoplasms.
This antibody does not recognize intermediate filament proteins.
Specificity | Cytokeratin-7 (CK7) |
---|---|
Species Reactivity | Human |
Host / Source | Mouse |
Isotype | IgG1 |
Application | IHC-F, IHC-P |
Clone | OV-TL 12/30 |
Antigen | Human Cytokeratin-7 (CK7) |
Quantity | 0, 5 ml |
Format | Purified |
Storage Temperature | -20 °C |
Shipping Temperature | 2-8 °C |