Mouse anti-Human PAP (Prostatic Acid Phosphatase) (unconjugated), Clone PAP29, IgG2a, Ready-to-use
Ready-to-use Antibody for Immunohistochemistry
Human prostate-specific acid phosphatase (PAP, EC 220.127.116.11) is an isoenzyme of acid phosphatase and catalyzes the hydrolysis of phosphoric acid esters. PAP is present in large amounts in prostatic gland tissue and seminal fluid. Other isoforms of the enzyme are found in erythrocytes, leukocytes, kidneys, bone, spleen, pancreas, and liver.
PAP is an enzyme with a molecular weight of approximately 100 kDa, consisting of two identical sub-enzymes of 48 kDa. PAP is present in large amounts in the epithelial cells of the prostate gland and its excretory ducts. In smaller amounts, PAP also appears to be present in pancreatic islets, parietal cells of the stomach, renal tubules, ureteral epithelium, and male anal glands and scattered cells in the rectum (2,3).
The enzyme is also detected in benign and malignant prostate tumors.
PAP (Prostatic Acid Phosphatase)
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Human PAP (Prostatic Acid Phosphatase)